Anti-inflammatory Activity of Azima tetracantha Root Bark Extract in Rats

نویسندگان

چکیده

Inflammation is associated with many pathological conditions such as arthritis, inflammatory bowel syndrome, cancer, etc. The side effects the long term use of current anti-inflammatory drugs necessitates need for development new drug fewer effects. present study was aimed at evaluating anti-oxidant and activity Azima tetracantha root bark, a plant widely used by tribal people in Siddha medicine treatment arthritis rheumatism. Aqueous methanolic extracts bark were prepared. Total phenol, flavoid, alkaloid, terpenoid saponin content analyzed. determined DPPH assay total antioxidant capacity. evaluated carrageenan induced paw edema model rats. phenol flavonoid contents higher extract compared to aqueous extract. found have dose-dependent both male female rats highest average inhibition 400 mg/kg. results confirm traditional this against disorders could be source novel drugs.

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ژورنال

عنوان ژورنال: Indian Journal of Animal Research

سال: 2023

ISSN: ['0367-6722', '0976-0555']

DOI: https://doi.org/10.18805/ijar.b-5068